05.05.2010, 16:39
The aim of this diploma project is to determine novel immune defense mechanisms against the consequences of oxidative stress. To achieve this goal we will employ molecular and cell biology as well as in vivo animal model systems. The thesis will focus on the characterization of inflammatory pathways triggered by products of oxidative stress in vitro. Promising observations will be followed up in vivo using mouse models. We will provide numerous different techniques including:
– Generation of oxidatively modified model proteins
– Tissue culture with primary as well as immortalized cells
– ELISA
– flow cytometry
– isolation of circulating microparticles from human plasma
– Real Time PCR
– Foam cell formation assay
– Mouse techniques: basic handling and breeding
intraperitoneal and intranasal injection
peritoneal and bronchoalveolar lavage
The successful candidate will be integrated into an interdisciplinary team working on various aspects of atherosclerosis and innate immunity. We collaborate with excellent research groups and pharmaceutical companies in several countries. Good communication skills, independence, and a sense of responsibility are required. English is the working language.
We are currently moving and from June 2010 on, the lab will be located in a brand new building close to the General Hospital of Vienna.
The position will be available in June 2010 with scholarship support according to FWF-guidelines for one year. Applicants should submit a cover letter and CV. Short listed candidates will be notified and invited for interview. Late applications may be considered until the position has been filled. Applications should be addressed to:
christoph.binder@meduniwien.ac.at
– Generation of oxidatively modified model proteins
– Tissue culture with primary as well as immortalized cells
– ELISA
– flow cytometry
– isolation of circulating microparticles from human plasma
– Real Time PCR
– Foam cell formation assay
– Mouse techniques: basic handling and breeding
intraperitoneal and intranasal injection
peritoneal and bronchoalveolar lavage
The successful candidate will be integrated into an interdisciplinary team working on various aspects of atherosclerosis and innate immunity. We collaborate with excellent research groups and pharmaceutical companies in several countries. Good communication skills, independence, and a sense of responsibility are required. English is the working language.
We are currently moving and from June 2010 on, the lab will be located in a brand new building close to the General Hospital of Vienna.
The position will be available in June 2010 with scholarship support according to FWF-guidelines for one year. Applicants should submit a cover letter and CV. Short listed candidates will be notified and invited for interview. Late applications may be considered until the position has been filled. Applications should be addressed to:
christoph.binder@meduniwien.ac.at